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Enhancement of nitrosourea cytotoxicity by misonidazole in vitro: correlation with carbamoylating potential.

We have investigated the relationships between nitrosourea structure and physicochemical properties and the ability of misonidazole (MISO) to potentiate nitrosourea cytotoxicity in an in vitro model system. EMT-6/Ro tumour cells were exposed in suspension to each of 9 different nitrosourea anti-tumo...

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Detalles Bibliográficos
Autores principales: Mulcahy, R. T., Dembs, N. L., Ublacker, G. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1984
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976738/
https://www.ncbi.nlm.nih.gov/pubmed/6704305