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Protection of cells from methotrexate toxicity by 7-hydroxymethotrexate.
Cell growth survival studies have revealed that 7-OH methotrexate is two orders of magnitude less cytotoxic to human melanoma and human acute lymphoblastic leukaemia (ALL) cells in vitro than methotrexate. The influence of 7-OH methotrexate on methotrexate toxicity was investigated by studying cell...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1984
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976804/ https://www.ncbi.nlm.nih.gov/pubmed/6590087 |