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Preclinical pharmacokinetics of benznidazole.

Benznidazole is a lipophilic analogue of misonidazole (MISO) which shows promise as a chemosensitizer for clinical use, particularly in combination with CCNU. We have investigated the detailed pharmacokinetics of benznidazole in mice, dogs and sheep to provide a data base for the estimation of doses...

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Detalles Bibliográficos
Autores principales: Workman, P., White, R. A., Walton, M. I., Owen, L. N., Twentyman, P. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1984
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976805/
https://www.ncbi.nlm.nih.gov/pubmed/6466543