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Preclinical pharmacokinetics of benznidazole.
Benznidazole is a lipophilic analogue of misonidazole (MISO) which shows promise as a chemosensitizer for clinical use, particularly in combination with CCNU. We have investigated the detailed pharmacokinetics of benznidazole in mice, dogs and sheep to provide a data base for the estimation of doses...
Autores principales: | Workman, P., White, R. A., Walton, M. I., Owen, L. N., Twentyman, P. R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1984
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976805/ https://www.ncbi.nlm.nih.gov/pubmed/6466543 |
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