The influence of serum methotrexate concentrations and drug dosage on outcome in childhood acute lymphoblastic leukaemia.

Sequential methotrexate (Mtx) absorption studies were undertaken in 127 children undergoing treatment for childhood non-T acute lymphoblastic leukaemia (ALL) to determine whether serum drug concentration, clearance and dosage affect event free survival (EFS). Higher serum concentration and area unde...

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Detalles Bibliográficos
Autores principales: Pearson, A. D., Amineddine, H. A., Yule, M., Mills, S., Long, D. R., Craft, A. W., Chessells, J. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977331/
https://www.ncbi.nlm.nih.gov/pubmed/1854617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977331/
https://www.ncbi.nlm.nih.gov/pubmed/1854617

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