Follow-up of retinoblastoma patients having prenatal and perinatal predictions for mutant gene carrier status using intragenic polymorphic probes from the RB1 gene.

We have carried out presymptomatic prediction of mutant gene carrier status in ten individuals with a family history of retinoblastoma. In all cases standard linkage studies were employed using intragenic DNA probes which recognise restriction fragment length polymorphisms. In four cases foetal DNA...

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Detalles Bibliográficos
Autores principales: Onadim, Z., Hungerford, J., Cowell, J. K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977377/
https://www.ncbi.nlm.nih.gov/pubmed/1350208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977377/
https://www.ncbi.nlm.nih.gov/pubmed/1350208

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