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Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests.

The influence of liver biochemistry tests on epirubicin pharmacokinetics has been investigated in 52 women with advanced breast cancer, 27 of whom had radiologically proven liver metastases. Patients received epirubicin 12.5-120 mg m-2 given as an i.v. bolus. Epirubicin levels were measured by HPLC...

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Detalles Bibliográficos
Autores principales: Twelves, C. J., Dobbs, N. A., Michael, Y., Summers, L. A., Gregory, W., Harper, P. G., Rubens, R. D., Richards, M. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977407/
https://www.ncbi.nlm.nih.gov/pubmed/1419619