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Histamine, leukotriene C4 and interleukin-2 increase antibody uptake into a human carcinoma xenograft model.

Systemically administered radiolabelled anti-tumour antibody is ineffective in treating the majority of patients with liver metastasis from colorectal carcinoma. We have assessed whether agents which increase capillary permeability can increase tumour uptake of antibody isotope conjugate. We develop...

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Detalles Bibliográficos
Autores principales: Hennigan, T. W., Begent, R. H., Allen-Mersh, T. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977450/
https://www.ncbi.nlm.nih.gov/pubmed/1931608