Tumour localisation with a radioactively labelled reshaped human monoclonal antibody.

A genetically reshaped human IgG1 monoclonal antibody (Hu2PLAP) with anti-tumour specificity, was radiolabelled with Indium-111 by chelation with a new macrocyclic compound (DOTA) which allows the production of stable radioimmunoconjugates for in vivo application. This was used to image seven patien...

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Detalles Bibliográficos
Autores principales: Hird, V., Verhoeyen, M., Badley, R. A., Price, D., Snook, D., Kosmas, C., Gooden, C., Bamias, A., Meares, C., Lavender, J. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977456/
https://www.ncbi.nlm.nih.gov/pubmed/1931615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977456/
https://www.ncbi.nlm.nih.gov/pubmed/1931615

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