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Monoclonal antibody FW6 generated against a mucin-carbohydrate of human amniotic fluid recognises a colonic tumour-associated epitope.

Mucus glycoproteins of human amniotic fluid were used to generate a monoclonal antibody (MAb) FW6, which stained the intestine of a 24 week stage fetus. In adults, 76% of colonic adenocarcinomas (13/17) showed strong expression of the FW6 epitope, but it was not detected in the histologically normal...

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Detalles Bibliográficos
Autores principales: Schwonzen, M., Schmits, R., Baldus, S. E., Vierbuchen, M., Hanisch, F. G., Pfreundschuh, M., Diehl, V., Bara, J., Uhlenbruck, G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977553/
https://www.ncbi.nlm.nih.gov/pubmed/1373294