Phorbol ester and bryostatin effects on growth and the expression of oestrogen responsive and TGF-beta 1 genes in breast tumour cells.

The phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) (10 nM) produce a marked reduction in the growth, measured by thymidine uptake, of MCF-7 cells in full growth medium, but had only a small effect on MDA-MB-231 and T47D cells. Bryostatin alone also inhibited growth but to a lesser extent...

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Detalles Bibliográficos
Autores principales: Nutt, J. E., Harris, A. L., Lunec, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977682/
https://www.ncbi.nlm.nih.gov/pubmed/1911215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977682/
https://www.ncbi.nlm.nih.gov/pubmed/1911215

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