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Human/mouse chimeric antibodies show low reactivity with human anti-murine antibodies (HAMA).

Human anti-murine antibody (HAMA) response is a serious problem in the repeated infusion of murine monoclonal antibodies (MoAbs). HAMA positive sera were obtained from seven patients with colorectal cancer, pancreas cancer, malignant melanoma or myocardial infarction who had previously received radi...

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Detalles Bibliográficos
Autores principales: Hosono, M., Endo, K., Sakahara, H., Watanabe, Y., Saga, T., Nakai, T., Kawai, C., Matsumori, A., Yamada, T., Watanabe, T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977718/
https://www.ncbi.nlm.nih.gov/pubmed/1739617