A phase I study on the reversal of multidrug resistance (MDR) in vivo: nifedipine plus etoposide.

Multidrug resistance (MDR) is one of the mechanisms of resistance to multiple cytotoxic drugs and is mediated by the expression of a membrane pump called the P-glycoprotein. Nifedipine is one of the calcium channel blocking agents which reverses MDR in vitro. Fifteen patients with various malignanci...

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Detalles Bibliográficos
Autores principales: Philip, P. A., Joel, S., Monkman, S. C., Dolega-Ossowski, E., Tonkin, K., Carmichael, J., Idle, J. R., Harris, A. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977739/
https://www.ncbi.nlm.nih.gov/pubmed/1739628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977739/
https://www.ncbi.nlm.nih.gov/pubmed/1739628

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