Monoclonal antibody targeting of methotrexate (MTX) against MTX-resistant tumour cell lines.

Several Methotrexate (MTX)-resistant sublines of the osteogenic sarcoma cell line 791T were derived by continuous selection in the presence of MTX and 12-O-tetradecanoylphorbol-13-acetate (TPA). Studies including assays of the uptake and binding of [3H]MTX and fluoresceinated-MTX, determined that th...

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Detalles Bibliográficos
Autores principales: Affleck, K., Embleton, M. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977768/
https://www.ncbi.nlm.nih.gov/pubmed/1616855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977768/
https://www.ncbi.nlm.nih.gov/pubmed/1616855

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