Therapeutic effect of the gastrin receptor antagonist, CR2093 on gastrointestinal tumour cell growth.

The gastrin receptor antagonist, CR2093, competed with 125I-gastrin-17 (5 x 10(-10) M) for binding to gastrin receptors on the rat pancreatic adenocarcinoma, AR42J (CR2093 concentration inducing 50% of 125I-gastrin-17 binding (IC50) was 8 x 10(-5) M), on the human gastric adenocarcinoma, MKN45 (IC50...

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Detalles Bibliográficos
Autores principales: Watson, S. A., Crosbee, D. M., Morris, D. L., Robertson, J. F., Makovec, F., Rovati, L. C., Hardcastle, J. D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977787/
https://www.ncbi.nlm.nih.gov/pubmed/1616859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977787/
https://www.ncbi.nlm.nih.gov/pubmed/1616859

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