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Immunohistological examination of the inter- and intracellular distribution of O6-alkylguanine DNA-alkyltransferase in human liver and melanoma.

The tissue and cellular distribution of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase) is an important question in relation to the response of tumour and normal tissues to chemotherapeutic regimes employing alkylating agents such as methyltriazenes and nitrosoureas. In order to...

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Detalles Bibliográficos
Autores principales: Lee, S. M., Rafferty, J. A., Elder, R. H., Fan, C. Y., Bromley, M., Harris, M., Thatcher, N., Potter, P. M., Altermatt, H. J., Perinat-Frey, T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977793/
https://www.ncbi.nlm.nih.gov/pubmed/1503911