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Cyclophosphamide decreases O6-alkylguanine-DNA alkyltransferase activity in peripheral lymphocytes of patients undergoing bone marrow transplantation.

O6-alkylguanine-DNA-alkyltransferase (ATase) levels were measured in extracts of peripheral blood lymphocytes taken at various times during chemotherapy from 19 patients with various haematological malignancies. Seven patients with advanced Hodgkin's disease received preparative treatment consi...

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Detalles Bibliográficos
Autores principales: Lee, S. M., Crowther, D., Scarffe, J. H., Dougal, M., Elder, R. H., Rafferty, J. A., Margison, G. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977821/
https://www.ncbi.nlm.nih.gov/pubmed/1387001