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Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours.

Cell killing can be achieved in an acidic environment in tissue culture (medium pH less than 7.0) by agents (nigericin, carbonylcyanide-3-chlorophenylhydrazone (CCCP)) which transport protons from the extracellular space into the cytoplasm. Cell killing is enhanced when these agents are used in comb...

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Detalles Bibliográficos
Autores principales: Newell, K., Wood, P., Stratford, I., Tannock, I.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977830/
https://www.ncbi.nlm.nih.gov/pubmed/1503904