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Radiolocalisation and imaging of stably HPLAP-transfected MO4 tumours with monoclonal antibodies and fragments.

Immunotargeting of PLAP-expressing tumours was studied for two radioiodinated, highly specific anti-PLAP monoclonal antibodies, 7E8 and 17E3, differing 10-fold in affinity, as well as for 7E8 F(ab')2 fragments. An anti-CEA monoclonal antibody or anti-CD3 F(ab')2 fragments were used as cont...

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Detalles Bibliográficos
Autores principales: Hendrix, P. G., Dauwe, S. E., Van De Voorde, A., Nouwen, E. J., Hoylaerts, M. F., De Broe, M. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977844/
https://www.ncbi.nlm.nih.gov/pubmed/1764368