Normal human breast xenografts activate N-nitrosodimethylamine: identification of potential target cells for an environmental nitrosamine.

Normal human breast tissue maintained as xenografts in female Balb/c (nu/nu) athymic mice is capable of metabolising N-nitrosodimethylamine (NDMA) to active intermediates that will react with DNA. Administration of NDMA to mice with slow-release implants of 17 beta-oestradiol which provide human phy...

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Detalles Bibliográficos
Autores principales: Zaidi, S. N., Laidlaw, I., Howell, A., Potten, C. S., Cooper, D. P., O'Connor, P. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977899/
https://www.ncbi.nlm.nih.gov/pubmed/1637681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977899/
https://www.ncbi.nlm.nih.gov/pubmed/1637681

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