O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.

The DNA repair enzyme, O6-alkylguanine-DNA-alkyltransferase (ATase), is thought to be the principal mechanism controlling resistance to nitrosoureas and related alkylating agents. We compared the sensitivities of five human testis and five bladder tumour cell lines to two nitrosoureas (N-nitroso-N-m...

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Detalles Bibliográficos
Autores principales: Walker, M. C., Masters, J. R., Margison, G. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978000/
https://www.ncbi.nlm.nih.gov/pubmed/1419626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978000/
https://www.ncbi.nlm.nih.gov/pubmed/1419626

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