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Structure of the SARS coronavirus main proteinase as an active C(2) crystallographic dimer
The 34 kDa main proteinase (M(pro)) from the severe acute respiratory syndrome coronavirus (SARS-CoV) plays an important role in the virus life cycle through the specific processing of viral polyproteins. As such, SARS-CoV M(pro) is a key target for the identification of specific inhibitors directed...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978130/ https://www.ncbi.nlm.nih.gov/pubmed/16511208 http://dx.doi.org/10.1107/S1744309105033257 |