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Structure of the SARS coronavirus main proteinase as an active C(2) crystallographic dimer

The 34 kDa main proteinase (M(pro)) from the severe acute respiratory syndrome coronavirus (SARS-CoV) plays an important role in the virus life cycle through the specific processing of viral polyproteins. As such, SARS-CoV M(pro) is a key target for the identification of specific inhibitors directed...

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Detalles Bibliográficos
Autores principales:	Xu, Ting, Ooi, Amy, Lee, Hooi Chen, Wilmouth, Rupert, Liu, Ding Xiang, Lescar, Julien
Formato:	Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2005
Materias:	Protein Structure Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978130/ https://www.ncbi.nlm.nih.gov/pubmed/16511208 http://dx.doi.org/10.1107/S1744309105033257

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