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The TCF7L2 locus and type 1 diabetes

BACKGROUND: TCF7L2 belongs to a subfamily of TCF7-like HMG box-containing transcription factors, and maps to human chromosome 10q25.3. A recent study identified genetic association of type 2 diabetes (T2D) with this gene, correlated with diminished insulin secretion. This study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Qu, Hui-Qi, Polychronakos, Constantin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978206/
https://www.ncbi.nlm.nih.gov/pubmed/17683561
http://dx.doi.org/10.1186/1471-2350-8-51