Cargando…

The TCF7L2 locus and type 1 diabetes

BACKGROUND: TCF7L2 belongs to a subfamily of TCF7-like HMG box-containing transcription factors, and maps to human chromosome 10q25.3. A recent study identified genetic association of type 2 diabetes (T2D) with this gene, correlated with diminished insulin secretion. This study aimed to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Hui-Qi, Polychronakos, Constantin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978206/ https://www.ncbi.nlm.nih.gov/pubmed/17683561 http://dx.doi.org/10.1186/1471-2350-8-51

Ejemplares similares

The TCF7L2 Locus: A Genetic Window Into the Pathogenesis of Type 1 and Type 2 Diabetes
por: Grant, Struan F.A.
Publicado: (2019)

The Role of TCF7L2 in Type 2 Diabetes
por: del Bosque-Plata, Laura, et al.
Publicado: (2021)

An in vivo cis-Regulatory Screen at the Type 2 Diabetes Associated TCF7L2 Locus Identifies Multiple Tissue-Specific Enhancers
por: Savic, Daniel, et al.
Publicado: (2012)

TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
por: Holstein, Andreas, et al.
Publicado: (2011)

TCF7L2 Variation and Proliferative Diabetic Retinopathy
por: Luo, Jing, et al.
Publicado: (2013)

TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes
por: Redondo, Maria J., et al.
Publicado: (2018)

Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes
por: Pang, D.X., et al.
Publicado: (2013)

Weak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population
por: Alsmadi, Osama, et al.
Publicado: (2008)

Association of TCF7L2 Genetic Polymorphisms with Type 2 Diabetes Mellitus in the Uygur Population of China
por: Yao, Hua, et al.
Publicado: (2015)

Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes
por: Ferreira, Mari Cassol, et al.
Publicado: (2019)

Habenular Tcf7l2 links nicotine addiction to diabetes
por: Duncan, Alexander, et al.
Publicado: (2019)

TCF7L2 polymorphisms are associated with amygdalar volume in elderly individuals with Type 2 Diabetes
por: Ganmore, Ithamar, et al.
Publicado: (2019)

The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes
por: del Bosque‐Plata, Laura, et al.
Publicado: (2021)

Tcf7l2/Tcf4 Transcriptional Repressor Function Requires HDAC Activity in the Developing Vertebrate CNS
por: Wang, Hui, et al.
Publicado: (2016)

No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect
por: Mathiesen, David S, et al.
Publicado: (2020)

Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice
por: Yang, Hyekyung, et al.
Publicado: (2012)

Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes
por: Redondo, Maria J, et al.
Publicado: (2014)

Replication of TCF7L2 rs7903146 association with type 2 diabetes in an Iranian population
por: Amoli, Mahsa M., et al.
Publicado: (2010)

Common variants in TCF7L2 and CDKAL1 genes and risk of type 2 diabetes mellitus in Egyptians
por: El-Lebedy, Dalia, et al.
Publicado: (2016)

Single Nucleotide Polymorphisms of TCF7L2 Are Linked to Diabetic Coronary Atherosclerosis
por: Muendlein, Axel, et al.
Publicado: (2011)

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes
por: Hindy, G., et al.
Publicado: (2012)

Association of the rs11196218 polymorphism in TCF7L2 with type 2 diabetes mellitus in Asian population
por: Zhai, Yujia, et al.
Publicado: (2014)

Alternative Splicing of TCF7L2 Gene in Omental and Subcutaneous Adipose Tissue and Risk of Type 2 Diabetes
por: Prokunina-Olsson, Ludmila, et al.
Publicado: (2009)

The TCF7L2 rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population
por: Ouhaibi-Djellouli, Hadjira, et al.
Publicado: (2014)

Meta-analysis of association between TCF7L2 polymorphism rs7903146 and type 2 diabetes mellitus
por: Ding, Weiyue, et al.
Publicado: (2018)

TCF7L2: the biggest story in diabetes genetics since HLA?
por: Zeggini, E., et al.
Publicado: (2006)

Limited TCF7L2 Expression in MS Lesions
por: Lürbke, Alexander, et al.
Publicado: (2013)

Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in β-Cell Function
por: Gloyn, Anna L., et al.
Publicado: (2009)

Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants
por: Redondo, Maria J., et al.
Publicado: (2022)

Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus
por: Rattanatham, Rujikorn, et al.
Publicado: (2021)

Association of the Type 2 Diabetes Mellitus Susceptibility Gene, TCF7L2, with Schizophrenia in an Arab-Israeli Family Sample
por: Alkelai, Anna, et al.
Publicado: (2012)

Meta-analysis of associations between TCF7L2 polymorphisms and risk of type 2 diabetes mellitus in the Chinese population
por: Wang, Jinjin, et al.
Publicado: (2013)

Contribution of the TCF7L2 rs7903146 (C/T) gene polymorphism to the susceptibility to type 2 diabetes mellitus in Cameroon
por: Guewo-Fokeng, Magellan, et al.
Publicado: (2015)

Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes
por: Qu, Hui-Qi, et al.
Publicado: (2008)

Polymorphisms in TCF7L2 gene are associated with gestational diabetes mellitus in Chinese Han population
por: Ye, Dan, et al.
Publicado: (2016)

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population
por: Melzer, David, et al.
Publicado: (2006)

Role of EPO and TCF7L2 Gene Polymorphism Contribution to the Occurrence of Diabetic Retinopathy
por: Liu, Chao, et al.
Publicado: (2022)

Cofilin 1 promotes bladder cancer and is regulated by TCF7L2
por: Wang, Fei, et al.
Publicado: (2017)

TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action
por: Villareal, Dennis T., et al.
Publicado: (2010)

Association of TCF7L2 Variants in Type 2 Diabetes Mellitus with Hypertriglyceridemia – A Case-Control Study
por: Gunavathy, Nagarajan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jscdtmod2d7m3f291hee4va612