Cargando…

MVB-12, a Fourth Subunit of Metazoan ESCRT-I, Functions in Receptor Downregulation

After ligand binding and endocytosis, cell surface receptors can continue to signal from endosomal compartments until sequestered from the cytoplasm. An important mechanism for receptor downregulation in vivo is via the inward budding of receptors into intralumenal vesicles to form specialized endos...

Descripción completa

Detalles Bibliográficos
Autores principales: Audhya, Anjon, McLeod, Ian X., Yates, John R., Oegema, Karen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978536/
https://www.ncbi.nlm.nih.gov/pubmed/17895996
http://dx.doi.org/10.1371/journal.pone.0000956