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TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study

BACKGROUND: Histological phenotype and clinical behaviour of malignant tumours are not only dependent on alterations in the epithelial cell compartment, but are affected by their interaction with inflammatory cells and tumour-associated stroma. Studies in animal models have shown influence of tumour...

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Detalles Bibliográficos
Autores principales: Bacman, David, Merkel, Susanne, Croner, Roland, Papadopoulos, Thomas, Brueckl, Wolfgang, Dimmler, Arno
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988827/
https://www.ncbi.nlm.nih.gov/pubmed/17692120
http://dx.doi.org/10.1186/1471-2407-7-156