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Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis

BACKGROUND: Interferon-α (IFN-α) is one of the central agents in immunotherapy for renal cell carcinoma (RCC) and binds to the IFN-α receptor (IFNAR). We investigated the role of IFNAR in RCC. METHODS: We quantified IFNAR mRNA expression in paired tumor and non-tumor samples from the surgical specim...

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Detalles Bibliográficos
Autores principales: Kamai, Takao, Yanai, Yoshiaki, Arai, Kyoko, Abe, Hideyuki, Yamanishi, Tomonori, Kurimoto, Masashi, Yoshida, Ken-Ichiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988828/
https://www.ncbi.nlm.nih.gov/pubmed/17697365
http://dx.doi.org/10.1186/1471-2407-7-159