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Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is usually constitutively activated in a variety of malignancies. Therefore, STAT3 may be a promising target for treatment of tumor cells. To explore the possibility of a double-stranded decoy oligodeoxynucleotide (ODN) targeted...

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Detalles Bibliográficos
Autores principales: Zhang, Xulong, Zhang, Jian, Wang, Lihua, Wei, Haiming, Tian, Zhigang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988829/
https://www.ncbi.nlm.nih.gov/pubmed/17683579
http://dx.doi.org/10.1186/1471-2407-7-149