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Nanoliter Reactors Improve Multiple Displacement Amplification of Genomes from Single Cells
Since only a small fraction of environmental bacteria are amenable to laboratory culture, there is great interest in genomic sequencing directly from single cells. Sufficient DNA for sequencing can be obtained from one cell by the Multiple Displacement Amplification (MDA) method, thereby eliminating...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988849/ https://www.ncbi.nlm.nih.gov/pubmed/17892324 http://dx.doi.org/10.1371/journal.pgen.0030155 |