Excitability Constraints on Voltage-Gated Sodium Channels

We study how functional constraints bound and shape evolution through an analysis of mammalian voltage-gated sodium channels. The primary function of sodium channels is to allow the propagation of action potentials. Since Hodgkin and Huxley, mathematical models have suggested that sodium channel pro...

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Detalles Bibliográficos
Autores principales: Angelino, Elaine, Brenner, Michael P
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988852/
https://www.ncbi.nlm.nih.gov/pubmed/17892320
http://dx.doi.org/10.1371/journal.pcbi.0030177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988852/
https://www.ncbi.nlm.nih.gov/pubmed/17892320
http://dx.doi.org/10.1371/journal.pcbi.0030177

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