Insight into the Folding Inhibition of the HIV-1 Protease by a Small Peptide

It has recently been shown that the highly protected segments 24–34 (S(2)) and 83–93 (S(8)) of each of the two 99-mers of human immunodeficiency virus type 1 protease play an essential role in the folding of the monomers, giving rise to the so-called (postcritical) folding nucleus ((FN) minimum cond...

Descripción completa

Detalles Bibliográficos
Autores principales: Bonomi, Massimiliano, Gervasio, Francesco L., Tiana, Guido, Provasi, Davide, Broglia, Ricardo A., Parrinello, Michele
Formato: Texto
Lenguaje:English
Publicado: Biophysical Society 2007
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989711/
https://www.ncbi.nlm.nih.gov/pubmed/17573430
http://dx.doi.org/10.1529/biophysj.107.106369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989711/
https://www.ncbi.nlm.nih.gov/pubmed/17573430
http://dx.doi.org/10.1529/biophysj.107.106369

Ejemplares similares