GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells

Apoptosis may be regulated by oxidants such as peroxynitrite (ONOO(−)). The tumour suppressor, p53, has been reported to play a crucial role in apoptosis induced by oxidants, therefore we assessed the ability of a ONOO(−) donor, GEA 3162, to activate caspases and induce mitochondrial permeability in...

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Detalles Bibliográficos
Autores principales: Taylor, Emma L., Li, John T., Tupper, Joan C., Rossi, Adriano G., Winn, Robert K., Harlan, John M.
Formato: Texto
Lenguaje:English
Publicado: 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991334/
https://www.ncbi.nlm.nih.gov/pubmed/17681284
http://dx.doi.org/10.1016/j.bcp.2007.06.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991334/
https://www.ncbi.nlm.nih.gov/pubmed/17681284
http://dx.doi.org/10.1016/j.bcp.2007.06.028

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