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Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine

BACKGROUND: One of the big roadblocks in development of HIV-1/AIDS vaccines is the enormous diversity of HIV-1, which could limit the value of any HIV-1 vaccine candidate currently under test. METHODOLOGY AND FINDINGS: To address the HIV-1 variation, we designed a novel T cell immunogen, designated...

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Detalles Bibliográficos
Autores principales: Létourneau, Sven, Im, Eung-Jun, Mashishi, Tumelo, Brereton, Choechoe, Bridgeman, Anne, Yang, Hongbing, Dorrell, Lucy, Dong, Tao, Korber, Bette, McMichael, Andrew J., Hanke, Tomáš
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991584/
https://www.ncbi.nlm.nih.gov/pubmed/17912361
http://dx.doi.org/10.1371/journal.pone.0000984