Deletion of Genes Implicated in Protecting the Integrity of Male Germ Cells Has Differential Effects on the Incidence of DNA Breaks and Germ Cell Loss

BACKGROUND: Infertility affects ∼20% of couples in Europe and in 50% of cases the problem lies with the male partner. The impact of damaged DNA originating in the male germ line on infertility is poorly understood but may increase miscarriage. Mouse models allow us to investigate how deficiencies in...

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Detalles Bibliográficos
Autores principales: Paul, Catriona, Povey, Joanne E., Lawrence, Nicola J., Selfridge, Jim, Melton, David W., Saunders, Philippa T. K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991594/
https://www.ncbi.nlm.nih.gov/pubmed/17912366
http://dx.doi.org/10.1371/journal.pone.0000989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991594/
https://www.ncbi.nlm.nih.gov/pubmed/17912366
http://dx.doi.org/10.1371/journal.pone.0000989

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