Cargando…
Deletion of Genes Implicated in Protecting the Integrity of Male Germ Cells Has Differential Effects on the Incidence of DNA Breaks and Germ Cell Loss
BACKGROUND: Infertility affects ∼20% of couples in Europe and in 50% of cases the problem lies with the male partner. The impact of damaged DNA originating in the male germ line on infertility is poorly understood but may increase miscarriage. Mouse models allow us to investigate how deficiencies in...
Autores principales: | Paul, Catriona, Povey, Joanne E., Lawrence, Nicola J., Selfridge, Jim, Melton, David W., Saunders, Philippa T. K. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991594/ https://www.ncbi.nlm.nih.gov/pubmed/17912366 http://dx.doi.org/10.1371/journal.pone.0000989 |
Ejemplares similares
-
Modelling germ cell development in vitro
por: Childs, Andrew J., et al.
Publicado: (2008) -
Transgenic Rescue of Spermatogenesis in Males With Mgat1 Deleted in Germ Cells
por: Biswas, Barnali, et al.
Publicado: (2020) -
Laminin in the male germ cells of Drosophila
Publicado: (1992) -
BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells
por: Kim, Byunghyuk, et al.
Publicado: (2016) -
Dynamics of male canine germ cell development
por: de Souza, Aline F., et al.
Publicado: (2018)