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Effect of Cellular Quiescence on the Success of Targeted CML Therapy
BACKGROUND: Similar to tissue stem cells, primitive tumor cells in chronic myelogenous leukemia have been observed to undergo quiescence; that is, the cells can temporarily stop dividing. Using mathematical models, we investigate the effect of cellular quiescence on the outcome of therapy with targe...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991595/ https://www.ncbi.nlm.nih.gov/pubmed/17912367 http://dx.doi.org/10.1371/journal.pone.0000990 |