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Review of fondaparinux sodium injection for the prevention of venous thromboembolism in patients undergoing surgery
The antithrombin binding sequence of heparin, a pentasaccharide, has been synthesized as fondaparinux, an indirect, selective, and reversible factor Xa inhibitor. It can be administered subcutaneously, is well absorbed, and has a half-life of c. 17 hours permitting once-daily injection. It has been...
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994024/ https://www.ncbi.nlm.nih.gov/pubmed/17323590 |