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A review of sitaxsentan sodium in patients with pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which eventually leads to fatal right heart failure. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, is increased in the pulmonary arteries of patients with pulmonary hypertension. Endothelin-1 acts through the...

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Detalles Bibliográficos
Autor principal: Waxman, Aaron B
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994033/
https://www.ncbi.nlm.nih.gov/pubmed/17583185