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A review of sitaxsentan sodium in patients with pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which eventually leads to fatal right heart failure. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, is increased in the pulmonary arteries of patients with pulmonary hypertension. Endothelin-1 acts through the...
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994033/ https://www.ncbi.nlm.nih.gov/pubmed/17583185 |