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Modulation of Aire regulates the expression of tissue-restricted antigens

Intrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune regulator (Aire) has been suggested in this process. The aim of this study was to establish whether down or up-regulati...

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Detalles Bibliográficos
Autores principales: Kont, Vivian, Laan, Martti, Kisand, Kai, Merits, Andres, Scott, Hamish S., Peterson, Pärt
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994210/
https://www.ncbi.nlm.nih.gov/pubmed/17599412
http://dx.doi.org/10.1016/j.molimm.2007.05.014