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Modulation of Aire regulates the expression of tissue-restricted antigens
Intrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune regulator (Aire) has been suggested in this process. The aim of this study was to establish whether down or up-regulati...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994210/ https://www.ncbi.nlm.nih.gov/pubmed/17599412 http://dx.doi.org/10.1016/j.molimm.2007.05.014 |