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Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis

It has unambiguously been shown that genetic, environmental, demographic, and technical factors may have substantial effects on gene expression levels. In addition to the measured variable(s) of interest, there will tend to be sources of signal due to factors that are unknown, unmeasured, or too com...

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Detalles Bibliográficos
Autores principales: Leek, Jeffrey T, Storey, John D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994707/
https://www.ncbi.nlm.nih.gov/pubmed/17907809
http://dx.doi.org/10.1371/journal.pgen.0030161