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Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis
It has unambiguously been shown that genetic, environmental, demographic, and technical factors may have substantial effects on gene expression levels. In addition to the measured variable(s) of interest, there will tend to be sources of signal due to factors that are unknown, unmeasured, or too com...
Autores principales: | Leek, Jeffrey T, Storey, John D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994707/ https://www.ncbi.nlm.nih.gov/pubmed/17907809 http://dx.doi.org/10.1371/journal.pgen.0030161 |
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