CpG Island Methylation in a Mouse Model of Lymphoma Is Driven by the Genetic Configuration of Tumor Cells

Hypermethylation of CpG islands is a common epigenetic alteration associated with cancer. Global patterns of hypermethylation are tumor-type specific and nonrandom. The biological significance and the underlying mechanisms of tumor-specific aberrant promoter methylation remain unclear, but some evid...

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Detalles Bibliográficos
Autores principales: Opavsky, Rene, Wang, Shu-Huei, Trikha, Prashant, Raval, Aparna, Huang, Yuan, Wu, Yue-Zhong, Rodriguez, Benjamin, Keller, Benjamin, Liyanarachchi, Sandya, Wei, Guo, Davuluri, Ramana V, Weinstein, Michael, Felsher, Dean, Ostrowski, Michael, Leone, Gustavo, Plass, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994712/
https://www.ncbi.nlm.nih.gov/pubmed/17907813
http://dx.doi.org/10.1371/journal.pgen.0030167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994712/
https://www.ncbi.nlm.nih.gov/pubmed/17907813
http://dx.doi.org/10.1371/journal.pgen.0030167

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