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Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
BACKGROUND: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental technologies, gene expression microarrays and Chromatin Immuno-Precipitation on Chip (ChIP-chip), are capable of producin...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994961/ https://www.ncbi.nlm.nih.gov/pubmed/17683565 http://dx.doi.org/10.1186/1471-2105-8-283 |