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Viral Oncogene–Induced DNA Damage Response Is Activated in Kaposi Sarcoma Tumorigenesis

Kaposi sarcoma is a tumor consisting of Kaposi sarcoma herpesvirus (KSHV)–infected tumor cells that express endothelial cell (EC) markers and viral genes like v-cyclin, vFLIP, and LANA. Despite a strong link between KSHV infection and certain neoplasms, de novo virus infection of human primary cells...

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Detalles Bibliográficos
Autores principales: Koopal, Sonja, Furuhjelm, Johanna H, Järviluoma, Annika, Jäämaa, Sari, Pyakurel, Pawan, Pussinen, Christel, Wirzenius, Maria, Biberfeld, Peter, Alitalo, Kari, Laiho, Marikki, Ojala, Päivi M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994968/
https://www.ncbi.nlm.nih.gov/pubmed/17907806
http://dx.doi.org/10.1371/journal.ppat.0030140