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The Origins of Specificity in Polyketide Synthase Protein Interactions

Polyketides, a diverse group of heteropolymers with antibiotic and antitumor properties, are assembled in bacteria by multiprotein chains of modular polyketide synthase (PKS) proteins. Specific protein–protein interactions determine the order of proteins within a multiprotein chain, and thereby the...

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Detalles Bibliográficos
Autores principales: Thattai, Mukund, Burak, Yoram, Shraiman, Boris I
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994986/
https://www.ncbi.nlm.nih.gov/pubmed/17907798
http://dx.doi.org/10.1371/journal.pcbi.0030186