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Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells

BACKGROUND: Tumors expressing a transforming growth factor-beta type I receptor (TβRI) mutant with sequence deletions in a nine-alanine (9A) stretch of the signal peptide are reported to be highly associated with disease progression. Expression of this mutant could interfere with endogenous TGFβ sig...

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Detalles Bibliográficos
Autores principales: Chen, Kuo-Li, Liu, Wan-Hsin, Yang, Yi-Yuan, Leu, Sy-Jye C, Shih, Neng-Yao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995218/
https://www.ncbi.nlm.nih.gov/pubmed/17705854
http://dx.doi.org/10.1186/1471-2199-8-72