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The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

The circumsporozoite protein (CSP) is the major surface protein of Plasmodium sporozoites, the infective stage of malaria. Although CSP has been extensively studied as a malaria vaccine candidate, little is known about its structure. Here, we show that CSP is proteolytically cleaved by a papain fami...

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Detalles Bibliográficos
Autores principales: Coppi, Alida, Pinzon-Ortiz, Consuelo, Hutter, Christina, Sinnis, Photini
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995445/
https://www.ncbi.nlm.nih.gov/pubmed/15630135
http://dx.doi.org/10.1084/jem.20040989