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The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion
The circumsporozoite protein (CSP) is the major surface protein of Plasmodium sporozoites, the infective stage of malaria. Although CSP has been extensively studied as a malaria vaccine candidate, little is known about its structure. Here, we show that CSP is proteolytically cleaved by a papain fami...
Autores principales: | Coppi, Alida, Pinzon-Ortiz, Consuelo, Hutter, Christina, Sinnis, Photini |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995445/ https://www.ncbi.nlm.nih.gov/pubmed/15630135 http://dx.doi.org/10.1084/jem.20040989 |
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